Non-pharmacologic interventions for long-term chronic insomnia

Purpose: To systematically review, analyze and synthesize empirical evidence that has been published regarding the effectiveness of non-pharmacological management for patients with chronic insomnia

Simultaneous quantization of bulk conduction and valence states through adsorption of nonmagnetic impurities on Bi2Se3

Exposing the (111) surface of the topological insulator Bi2Se3 to carbon monoxide results in strong shifts of the features observed in angle-resolved photoemission. The behavior is very similar to an often reported `aging' effect of the surface and it is concluded that this aging is most likely due to the adsorption of rest gas molecules. The spectral changes are also similar to those recently reported in connection with the adsorption of the magnetic adatom Fe. All spectral changes can be explained by a simultaneous confinement of the conduction band and valence band states. This is only possible because of the unusual bulk electronic structure of Bi2Se3. The valence band quantization leads to spectral features which resemble those of a band gap opening at the Dirac point.Comment: 5 pages, 4 figure

Comparing the Heterogeneity of Copper-Binding Characteristics for Two Different-Sized Soil Humic Acid Fractions Using Fluorescence Quenching Combined with 2D-COS

Heterogeneous distributions of copper-binding characteristics were compared for two ultrafiltered size fractions of a soil HA using fluorescence quenching combined with two-dimensional correlation spectroscopy (2D-COS). The apparent shapes of the original synchronous fluorescence spectra and the extent of the fluorescence quenching upon the addition of copper were similar for the two fractions. The stability constants calculated at their highest peaks were not significantly different. However, the 2D-COS results revealed that the fluorescence quenching behaviors were strongly affected by the associated wavelengths and the fraction's size. The spectral change preferentially occurred in the wavelength order of 467 nm → 451 nm → 357 nm for the 1–10 K fraction and of 376 nm → 464 nm for the >100 K fraction. The extent of the binding affinities exactly followed the sequential orders interpreted from the 2D-COS, and they exhibited the distinctive ranges of the logarithmic values from 5.86 to 4.91 and from 6.48 to 5.95 for the 1–10 K and the >100 K fractions, respectively. Our studies demonstrated that fluorescence quenching combined with 2D-COS could be successfully utilized to give insight into the chemical heterogeneity associated with metal-binding sites within the relatively homogeneous HA size fractions

Preliminary Phytochemical Analyses of Two Varieties of Adenia Lobata (Jacq) and the Antioxidant Activity of Their Various Solvent Fractions

Adenia lobata is a medicinal plant that is traditionally used for the treatment of various diseases such as cancer in some places in eastern Nigeria. Comparative phytochemical analyses were carried out on two varieties of Adenia lobata; Adenia lobata with cordate leaves (ALC) and Adenia lobata with palmate leaves (ALP). ALC was found to possess more phytochemical constituents than ALP. The antioxidant activity of the solvent fractions viz. hexane, dichloromethane (DCM), ethylacetate, butanol and aqueous fractions of each variety of the Adenia lobata was also determined. The highest antioxidant activity (63.87%) was found in the ethylacetate fraction of ALC. These results suggest that the therapeutic use of this plant in the treatment of cancer could be due to its antioxidant activity

A New Synergistic Forecasting Method for Short-Term Traffic Flow with Event-Triggered Strong Fluctuation

Directing against the shortcoming of low accuracy in short-term traffic flow prediction caused by strong traffic flow fluctuation, a novel method for short-term traffic forecasting based on the combination of improved grey Verhulst prediction algorithm and first-order difference exponential smoothing is proposed. Firstly, we constructed an improved grey Verhulst prediction model by introducing the Markov chain to its traditional version. Then, based on an introduced dynamic weighting factor, the improved grey Verhulst prediction method, and the first-order difference exponential smoothing technique, the new method for short-term traffic forecasting is completed in an efficient way. Finally, experiment and analysis are carried out in the light of actual data gathered from strong fluctuation environment to verify the effectiveness and rationality of our proposed scheme

Trends in Avoidable Death over 20 Years in Korea

To evaluate the achievement of health care services in Korea independent of other socioeconomic factors, we observed the time trend of avoidable death between 1983 and 2004. A list of avoidable causes of death was constructed based on the European Community Atlas of "Avoidable Death". We calculated sex- and age-standardized mortality rates of Korean aged 1-64 yr using data of the Korea National Statistical Office. The avoidable mortality rate (per 100,000 persons) decreased from 225 to 84 in men and from 122 to 41 in women. Accordingly, the proportion of avoidable deaths among all classifiable deaths was reduced by 8.1% in men and 6.4% in women. However, mortality rates from some preventable causes such as ischemic heart disease and malignant neoplasms of lung, breast, cervix, and colorectum have been on the rise. Mortality preventable by appropriate medical care showed the greatest reduction (by 77.8%), while the mortality preventable by primary prevention showed the least reduction (by 50.0%). These findings suggest that health care service has significantly contributed to the improvement of health in Korea. However, more effective intervention programs would be needed given the less reduction in mortality avoidable by primary or secondary prevention than expected and unexpectedly increasing mortality from several preventable causes